Targeting of TAM Receptors Ameliorates Fibrotic Mechanisms in Idiopathic Pulmonary Fibrosis

Rationale: Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant lung remodeling, which progressively abolishes lung function in an RTK (receptor tyrosine kinase)–dependent manner. Gas6 (growth arrest–specific 6) ligand, Tyro3 (TYRO3 protein tyrosine kinase 3), and Axl (anexelekto) RTK ex...

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Publicado en:Am J Respir Crit Care Med
Autores principales: Espindola, Milena S., Habiel, David M., Narayanan, Rohan, Jones, Isabelle, Coelho, Ana L., Murray, Lynne A., Jiang, Dianhua, Noble, Paul W., Hogaboam, Cory M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Thoracic Society 2018
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005556/
https://ncbi.nlm.nih.gov/pubmed/29634284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201707-1519OC
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