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Construction of homogeneous antibody–drug conjugates using site-selective protein chemistry

Systemic chemotherapy, the current standard of care for the treatment of cancer, is rarely curative and is often accompanied by debilitating side effects. Targeted drug delivery stands as an alternative to chemotherapy, with the potential to improve upon its low efficacy and systemic toxicity. Among...

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Vydáno v:Chem Sci
Hlavní autoři: Akkapeddi, Padma, Azizi, Saara-Anne, Freedy, Allyson M., Cal, Pedro M. S. D., Gois, Pedro M. P., Bernardes, Gonçalo J. L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005007/
https://ncbi.nlm.nih.gov/pubmed/29997785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00170j
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