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Computational Construction of Antibody–Drug Conjugates Using Surface Lysines as the Antibody Conjugation Site and a Non-cleavable Linker

Antibody–drug conjugates (ADCs) constitute a category of anticancer targeted therapy that has gathered great interest during the last few years because of their potential to kill cancer cells while causing significantly fewer side effects than traditional chemotherapy. In this paper, a process of co...

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Détails bibliographiques
Publié dans:Cancer Inform
Auteurs principaux: Filntisi, Arianna, Vlachakis, Dimitrios, Matsopoulos, George K, Kossida, Sophia
Format: Artigo
Langue:Inglês
Publié: Libertas Academica 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4260860/
https://ncbi.nlm.nih.gov/pubmed/25506200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/CIN.S19222
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