STING-Activating Adjuvants Elicit a Th17 Immune Response and Protect against Mycobacterium tuberculosis Infection

There are a limited number of adjuvants that elicit effective cell-based immunity required for protection against intracellular bacterial pathogens. Here, we report that STING-activating cyclic dinucleotides (CDNs) formulated in a protein subunit vaccine elicit long-lasting protective immunity to My...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Rep
Autors principals: Van Dis, Erik, Sogi, Kimberly M., Rae, Chris S., Sivick, Kelsey E., Surh, Natalie H., Leong, Meredith L., Kanne, David B., Metchette, Ken, Leong, Justin J., Bruml, Jacob R., Chen, Vivian, Heydari, Kartoosh, Cadieux, Nathalie, Evans, Tom, McWhirter, Sarah M., Dubensky, Thomas W., Portnoy, Daniel A., Stanley, Sarah A.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003617/
https://ncbi.nlm.nih.gov/pubmed/29719256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.003
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars