Inhibition of the Fibrinogen‐Like Protein 2:Fcγ RIIB/RIII immunosuppressive pathway enhances antiviral T‐cell and B‐cell responses leading to clearance of lymphocytic choriomeningitis virus clone 13

Persistent viruses evade immune detection by interfering with virus‐specific innate and adaptive antiviral immune responses. Fibrinogen‐like protein‐2 (FGL2) is a potent effector molecule of CD4(+) CD25(+) FoxP3(+) regulatory T cells and exerts its immunosuppressive activity following ligation to it...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Immunology
Main Authors: Luft, Olga, Khattar, Ramzi, Farrokhi, Kaveh, Ferri, Dario, Yavorska, Nataliya, Zhang, Jianhua, Sadozai, Hassan, Adeyi, Oyedele, Chruscinski, Andrzej, Levy, Gary A., Selzner, Nazia
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002236/
https://ncbi.nlm.nih.gov/pubmed/29341118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12897
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