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Anti-FcγRIIB mAb suppresses murine IgG-dependent anaphylaxis by Fc domain targeting of FcγRIII
BACKGROUND: The inhibitory receptor FcγRIIB is expressed on human and murine bone marrow–derived cells and limits inflammation by suppressing signaling through stimulatory receptors. OBJECTIVE: We sought to evaluate the effects of K9.361, a mouse IgG(2a) alloantibody to mouse FcγRIIB, on murine anap...
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| Publié dans: | J Allergy Clin Immunol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8215520/ https://ncbi.nlm.nih.gov/pubmed/28624610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.05.027 |
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