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Anti-FcγRIIB mAb suppresses murine IgG-dependent anaphylaxis by Fc domain targeting of FcγRIII

BACKGROUND: The inhibitory receptor FcγRIIB is expressed on human and murine bone marrow–derived cells and limits inflammation by suppressing signaling through stimulatory receptors. OBJECTIVE: We sought to evaluate the effects of K9.361, a mouse IgG(2a) alloantibody to mouse FcγRIIB, on murine anap...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Allergy Clin Immunol
Egile Nagusiak: Clay, Corey D., Strait, Richard T., Mahler, Ashley, Khodoun, Marat V., Finkelman, Fred D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215520/
https://ncbi.nlm.nih.gov/pubmed/28624610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.05.027
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