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Targeted Deletion of FGL2 Leads to Increased Early Viral Replication and Enhanced Adaptive Immunity in a Murine Model of Acute Viral Hepatitis Caused by LCMV WE

Mounting effective innate and adaptive immune responses are critical for viral clearance and the generation of long lasting immunity. It is known that production of inhibitory factors may result in the inability of the host to clear viruses, resulting in chronic viral persistence. Fibrinogen-like pr...

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Detalhes bibliográficos
Main Authors: Khattar, Ramzi, Luft, Olga, Yavorska, Nataliya, Shalev, Itay, Phillips, M. James, Adeyi, Oyedele, Gao, Darrin, Bartczak, Agata, Urbanellis, Peter, Shyu, Wendy, Zhang, Jianhua, Manuel, Justin, Levy, Gary A., Selzner, Nazia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3795679/
https://ncbi.nlm.nih.gov/pubmed/24146739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0072309
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