The regulatory T cell effector molecule fibrinogen-like protein 2 is necessary for the development of rapamycin-induced tolerance to fully MHC-mismatched murine cardiac allografts

Therapies that promote tolerance in solid organ transplantation will improve patient outcomes by eliminating the need for long-term immunosuppression. To investigate mechanisms of rapamycin-induced tolerance, C3H/HeJ mice were heterotopically transplanted with MHC-mismatched hearts from BALB/cJ mice...

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Pubblicato in:Immunology
Autori principali: Urbanellis, Peter, Shyu, Wendy, Khattar, Ramzi, Wang, Jihong, Zakharova, Anna, He, Wei, Sadozai, Hassan, Amir, Achiya Z, Shalev, Itay, Phillips, M James, Adeyi, Oyedele, Ross, Heather, Grant, David, Levy, Gary A, Chruscinski, Andrzej
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2015
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264913/
https://ncbi.nlm.nih.gov/pubmed/24990517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12354
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