MHC Mismatch Inhibits Neurogenesis and Neuron Maturation in Stem Cell Allografts

BACKGROUND: The role of histocompatibility and immune recognition in stem cell transplant therapy has been controversial, with many reports arguing that undifferentiated stem cells are protected from immune recognition due to the absence of major histocompatibility complex (MHC) markers. This argume...

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Autores principales: Chen, Zhiguo, Phillips, Lori K., Gould, Elizabeth, Campisi, Jay, Lee, Star W., Ormerod, Brandi K., Zwierzchoniewska, Monika, Martinez, Olivia M., Palmer, Theo D.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3068158/
https://ncbi.nlm.nih.gov/pubmed/21479168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014787
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