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Differential roles of TNFR1 and TNFR2 signaling in adult hippocampal neurogenesis
Tumor necrosis factor alpha (TNFα) is a potent inhibitor of neurogenesis in vitro but here we show that TNFα signaling has both positive and negative effects on neurogenesis in vivo and is required to moderate the negative impact of cranial irradiation on hippocampal neurogenesis. In vitro, basal le...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2013
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3641155/ https://ncbi.nlm.nih.gov/pubmed/23402793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2013.01.083 |
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