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Absence of CCL2 is sufficient to restore hippocampal neurogenesis following cranial irradiation

Cranial irradiation for the treatment of brain tumors causes a delayed and progressive cognitive decline that is pronounced in young patients. Dysregulation of neural stem and progenitor cells is thought to contribute to these effects by altering early childhood brain development. Earlier work has s...

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Autors principals: Lee, Star W., Haditsch, Ursula, Cord, Branden J., Guzman, Raphael, Kim, Soo Jeong, Boettcher, Chotima, Priller, Josef, Ormerod, Brandi K., Palmer, Theo D.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3556199/
https://ncbi.nlm.nih.gov/pubmed/23041279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2012.09.010
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