Overexpression of fibrinogen-like protein 2 protects against T cell-induced colitis

AIM: To determine the effect of overexpression of fibrinogen-like protein 2 (FGL2) on regulatory T cell (Treg) and effector T (Teff) cell function on T cell-induced colitis in Rag1(-/-) mice. METHODS: Treg and Teff cells from fgl2(-/-), fgl2(+/+), and fgl2(Tg) mice were purified by FACS. They were s...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Bartczak, Agata, Zhang, Jianhua, Adeyi, Oyedele, Amir, Achiya, Grant, David, Gorczynski, Reginald, Selzner, Nazia, Chruscinski, Andrzej, Levy, Gary A
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2017
Assuntos:
Basic Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403746/
https://ncbi.nlm.nih.gov/pubmed/28487604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i15.2673
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