Overexpression of fibrinogen-like protein 2 protects against T cell-induced colitis

AIM: To determine the effect of overexpression of fibrinogen-like protein 2 (FGL2) on regulatory T cell (Treg) and effector T (Teff) cell function on T cell-induced colitis in Rag1(-/-) mice. METHODS: Treg and Teff cells from fgl2(-/-), fgl2(+/+), and fgl2(Tg) mice were purified by FACS. They were s...

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Publicado en:World J Gastroenterol
Autores principales: Bartczak, Agata, Zhang, Jianhua, Adeyi, Oyedele, Amir, Achiya, Grant, David, Gorczynski, Reginald, Selzner, Nazia, Chruscinski, Andrzej, Levy, Gary A
Formato: Artigo
Lenguaje:Inglês
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Basic Study
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403746/
https://ncbi.nlm.nih.gov/pubmed/28487604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i15.2673
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