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Combination therapy of lovastatin and AMP‐activated protein kinase activator improves mitochondrial and peroxisomal functions and clinical disease in experimental autoimmune encephalomyelitis model
Recent studies report that loss and dysfunction of mitochondria and peroxisomes contribute to the myelin and axonal damage in multiple sclerosis (MS). In this study, we investigated the efficacy of a combination of lovastatin and AMP‐activated protein kinase (AMPK) activator (AICAR) on the loss and...
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| Publicado no: | Immunology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6002225/ https://ncbi.nlm.nih.gov/pubmed/29331024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12893 |
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