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Combinatorial Effect of Metformin and Lovastatin Impedes T-cell Autoimmunity and Neurodegeneration in Experimental Autoimmune Encephalomyelitis

Multiple Sclerosis (MS) is an incurable central nervous system (CNS) demyelinating disease affecting several million people worldwide. Due to the multifactorial and complex pathology of MS, FDA approved drugs often show limited efficacy inpatients. We earlier documented that both lovastatin (cholest...

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Hlavní autoři: Paintlia, Ajaib S, Mohan, Sarumathi, Singh, Inderjit
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855339/
https://ncbi.nlm.nih.gov/pubmed/24324917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-9899.1000149
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