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Inhibition of Rho Family Functions by Lovastatin Promotes Myelin Repair in Ameliorating Experimental Autoimmune Encephalomyelitis

Impaired remyelination is critical to neuroinflammation in multiple sclerosis (MS), which causes chronic and relapsing neurological impairments. Recent studies revealed that immunomodulatory activity of statins in an experimental autoimmune encephalomyelitis (EAE) model of MS are via depletion of is...

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Detalhes bibliográficos
Main Authors: Paintlia, Ajaib Singh, Paintlia, Manjeet Kaur, Singh, Avtar Kaur, Singh, Inderjit
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706586/
https://ncbi.nlm.nih.gov/pubmed/18239032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.044230
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