Inhibition of Rho Family Functions by Lovastatin Promotes Myelin Repair in Ameliorating Experimental Autoimmune Encephalomyelitis

Impaired remyelination is critical to neuroinflammation in multiple sclerosis (MS), which causes chronic and relapsing neurological impairments. Recent studies revealed that immunomodulatory activity of statins in an experimental autoimmune encephalomyelitis (EAE) model of MS are via depletion of is...

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Hlavní autoři: Paintlia, Ajaib Singh, Paintlia, Manjeet Kaur, Singh, Avtar Kaur, Singh, Inderjit
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706586/
https://ncbi.nlm.nih.gov/pubmed/18239032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.044230
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