Evaluation of bisulfite kits for DNA methylation profiling in terms of DNA fragmentation and DNA recovery using digital PCR

DNA methylation is one of the most important epigenetic modifications in the regulation of gene transcription. The current gold standard to study this modification is bisulfite sequencing. Although multiple commercial bisulfite treatment kits provide good conversion efficiencies, DNA loss and especi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Kint, Sam, De Spiegelaere, Ward, De Kesel, Jonas, Vandekerckhove, Linos, Van Criekinge, Wim
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6002050/
https://ncbi.nlm.nih.gov/pubmed/29902267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199091
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