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Underestimated effect of intragenic HIV-1 DNA methylation on viral transcription in infected individuals
BACKGROUND: The HIV-1 proviral genome harbors multiple CpG islands (CpGIs), both in the promoter and intragenic regions. DNA methylation in the promoter region has been shown to be heavily involved in HIV-1 latency regulation in cultured cells. However, its exact role in proviral transcriptional reg...
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| Publicat a: | Clin Epigenetics |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7049218/ https://ncbi.nlm.nih.gov/pubmed/32111236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-00829-1 |
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