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Quality Evaluation of Methyl Binding Domain Based Kits for Enrichment DNA-Methylation Sequencing
DNA-methylation is an important epigenetic feature in health and disease. Methylated sequence capturing by Methyl Binding Domain (MBD) based enrichment followed by second-generation sequencing provides the best combination of sensitivity and cost-efficiency for genome-wide DNA-methylation profiling....
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3598902/ https://ncbi.nlm.nih.gov/pubmed/23554971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059068 |
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