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Combining in silico prediction and ribosome profiling in a genome-wide search for novel putatively coding sORFs

BACKGROUND: It was long assumed that proteins are at least 100 amino acids (AAs) long. Moreover, the detection of short translation products (e.g. coded from small Open Reading Frames, sORFs) is very difficult as the short length makes it hard to distinguish true coding ORFs from ORFs occurring by c...

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Detalhes bibliográficos
Main Authors: Crappé, Jeroen, Van Criekinge, Wim, Trooskens, Geert, Hayakawa, Eisuke, Luyten, Walter, Baggerman, Geert, Menschaert, Gerben
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852105/
https://ncbi.nlm.nih.gov/pubmed/24059539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-648
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