Quality Evaluation of Methyl Binding Domain Based Kits for Enrichment DNA-Methylation Sequencing

DNA-methylation is an important epigenetic feature in health and disease. Methylated sequence capturing by Methyl Binding Domain (MBD) based enrichment followed by second-generation sequencing provides the best combination of sensitivity and cost-efficiency for genome-wide DNA-methylation profiling....

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Main Authors: De Meyer, Tim, Mampaey, Evi, Vlemmix, Michaël, Denil, Simon, Trooskens, Geert, Renard, Jean-Pierre, De Keulenaer, Sarah, Dehan, Pierre, Menschaert, Gerben, Van Criekinge, Wim
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3598902/
https://ncbi.nlm.nih.gov/pubmed/23554971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059068
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