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Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD

Amyotrophic lateral sclerosis (ALS) is characterized by a progressive degeneration of upper and lower motor neurons, resulting in fatal paralysis due to denervation of the muscle. Due to genetic, pathological and symptomatic overlap, ALS is now considered a spectrum disease together with frontotempo...

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Publicado en:Brain Res
Autores principales: Starr, Alexander, Sattler, Rita
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997509/
https://ncbi.nlm.nih.gov/pubmed/29453960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2018.02.011
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