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Testosterone Complex and Non-Steroidal Ligands of Human Aromatase

Cytochrome P450 aromatase (AROM) catalyzes the biosynthesis of estrogen from androgen. Previously crystal structures of human AROM in complex with the substrate androstenedione, and inhibitors exemestane, as well as the newly designed steroidal compounds, have been reported. Here we report the first...

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Detalles Bibliográficos
Publicado en:J Steroid Biochem Mol Biol
Autores principales: Ghosh, Debashis, Egbuta, Chinaza, Lo, Jessica
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997392/
https://ncbi.nlm.nih.gov/pubmed/29476820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2018.02.009
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