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Structural Basis for the Functional Roles of Critical Residues in Human Cytochrome P450 Aromatase
[Image: see text] Cytochrome P450 aromatase (CYP19A1) is the only enzyme known to catalyze the biosynthesis of estrogens from androgens. The crystal structure of human placental aromatase (pArom) has paved the way toward understanding the structure–function relationships of this remarkable enzyme. U...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799952/ https://ncbi.nlm.nih.gov/pubmed/23899247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400669h |
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