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Structural Basis for the Functional Roles of Critical Residues in Human Cytochrome P450 Aromatase

[Image: see text] Cytochrome P450 aromatase (CYP19A1) is the only enzyme known to catalyze the biosynthesis of estrogens from androgens. The crystal structure of human placental aromatase (pArom) has paved the way toward understanding the structure–function relationships of this remarkable enzyme. U...

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Détails bibliographiques
Auteurs principaux: Lo, Jessica, Di Nardo, Giovanna, Griswold, Jennifer, Egbuta, Chinaza, Jiang, Wenhua, Gilardi, Gianfranco, Ghosh, Debashis
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799952/
https://ncbi.nlm.nih.gov/pubmed/23899247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400669h
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