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Testosterone Complex and Non-Steroidal Ligands of Human Aromatase

Cytochrome P450 aromatase (AROM) catalyzes the biosynthesis of estrogen from androgen. Previously crystal structures of human AROM in complex with the substrate androstenedione, and inhibitors exemestane, as well as the newly designed steroidal compounds, have been reported. Here we report the first...

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Bibliografiske detaljer
Udgivet i:J Steroid Biochem Mol Biol
Main Authors: Ghosh, Debashis, Egbuta, Chinaza, Lo, Jessica
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5997392/
https://ncbi.nlm.nih.gov/pubmed/29476820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2018.02.009
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