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Recent Progress in the Discovery of Next Generation Inhibitors of Aromatase from the Structure–Function Perspective

Human aromatase catalyzes the synthesis of estrogen from androgen with high substrate specificity. For the past 40 years, aromatase has been a target of intense inhibitor discovery research for the prevention and treatment of estrogen-dependent breast cancer. The so-called third generation aromatase...

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Foilsithe in:J Med Chem
Main Authors: Ghosh, Debashis, Lo, Jessica, Egbuta, Chinaza
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915572/
https://ncbi.nlm.nih.gov/pubmed/26689671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.5b01281
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