Rational library design by functional CDR resampling

Successful antibody discovery relies on diversified libraries, where two aspects are implied, namely the absolute number of unique clones and the percentage of functional clones. Instead of pursuing the absolute quantity thresholded by current display technology, we have sought to maximize the effec...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:N Biotechnol
Autores principales: Zhao, Qi, Buhr, Diane, Gunter, Courtney, Frenette, Jenny, Ferguson, Mary, Sanford, Eric, Holland, Erika, Rajagopal, Chitra, Batonick, Melissa, Kiss, Margaret M., Weiner, Michael P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995609/
https://ncbi.nlm.nih.gov/pubmed/29242049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbt.2017.12.005
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares