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Platform for High-Throughput Antibody Selection using Synthetically-Designed Antibody Libraries

Synthetic humanized antibody libraries are frequently generated by random incorporation of changes at multiple positions in the antibody hypervariable regions. Although these libraries have very large theoretical diversities (>10(20)), the practical diversity that can be achieved by transformatio...

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Detalhes bibliográficos
Publicado no:N Biotechnol
Main Authors: Batonick, Melissa, Holland, Erika G., Busygina, Valeria, Alderman, Dawn, Kay, Brian K., Weiner, Michael P., Kiss, Margaret M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879119/
https://ncbi.nlm.nih.gov/pubmed/26607994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbt.2015.11.005
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