Rational library design by functional CDR resampling

Successful antibody discovery relies on diversified libraries, where two aspects are implied, namely the absolute number of unique clones and the percentage of functional clones. Instead of pursuing the absolute quantity thresholded by current display technology, we have sought to maximize the effec...

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Detaylı Bibliyografya
Yayımlandı:N Biotechnol
Asıl Yazarlar: Zhao, Qi, Buhr, Diane, Gunter, Courtney, Frenette, Jenny, Ferguson, Mary, Sanford, Eric, Holland, Erika, Rajagopal, Chitra, Batonick, Melissa, Kiss, Margaret M., Weiner, Michael P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995609/
https://ncbi.nlm.nih.gov/pubmed/29242049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbt.2017.12.005
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