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Rational library design by functional CDR resampling
Successful antibody discovery relies on diversified libraries, where two aspects are implied, namely the absolute number of unique clones and the percentage of functional clones. Instead of pursuing the absolute quantity thresholded by current display technology, we have sought to maximize the effec...
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| Veröffentlicht in: | N Biotechnol |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5995609/ https://ncbi.nlm.nih.gov/pubmed/29242049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbt.2017.12.005 |
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