Purpose-Oriented Antibody Libraries Incorporating Tailored CDR3 Sequences

The development of in vitro antibody selection technologies has allowed overcoming some limitations inherent to the hybridoma technology. In most cases, large repertoires of antibody genes have been assembled to create highly diversified libraries allowing the isolation of antibodies recognizing vir...

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Bibliografische gegevens
Hoofdauteurs: Pauline Bonvin, Sophie Venet, Marie Kosco-Vilbois, Nicolas Fischer
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2015-05-01
Reeks:Antibodies
Onderwerpen:
monoclonal antibody
phage display
antibody library
complementary determining region
cryptic site
pH-dependence
Online toegang:http://www.mdpi.com/2073-4468/4/2/103
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