De novo isolation of antibodies with pH-dependent binding properties

pH-dependent antibodies are engineered to release their target at a slightly acidic pH, a property making them suitable for clinical as well as biotechnological applications. Such antibodies were previously obtained by histidine scanning of pre-existing antibodies, a labor-intensive strategy resulti...

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Detalles Bibliográficos
Publicado en:MAbs
Main Authors: Bonvin, Pauline, Venet, Sophie, Fontaine, Gaëlle, Ravn, Ulla, Gueneau, Franck, Kosco-Vilbois, Marie, Proudfoot, Amanda El, Fischer, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2015
Assuntos:
Short Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4623423/
https://ncbi.nlm.nih.gov/pubmed/25608219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1006993
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