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Dual Specificity of Anti-CXCL10-CXCL9 Antibodies Is Governed by Structural Mimicry
Dual-specific antibodies are characterized by an antigen-combining site mediating specific interactions with two different antigens. We have generated five dual-specific single chain variable fragments (scFv) that neutralize the activity of the two chemokines, CXCL9 and CXCL10, to bind to their rece...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3256858/ https://ncbi.nlm.nih.gov/pubmed/22041899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.253658 |
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