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Comparing CDRH3 diversity captured from secondary lymphoid organs for the generation of recombinant human antibodies
The plasticity of natural immunoglobulin repertoires can be exploited for the generation of phage display libraries. Secondary lymphoid organs, such as the spleen and the lymph nodes, constitute interesting sources of diversity because they are rich in B cells, part of which can be affinity matured....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3851222/ https://ncbi.nlm.nih.gov/pubmed/23924800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.25592 |
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