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Platform for High-Throughput Antibody Selection using Synthetically-Designed Antibody Libraries

Synthetic humanized antibody libraries are frequently generated by random incorporation of changes at multiple positions in the antibody hypervariable regions. Although these libraries have very large theoretical diversities (>10(20)), the practical diversity that can be achieved by transformatio...

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書目詳細資料
發表在:N Biotechnol
Main Authors: Batonick, Melissa, Holland, Erika G., Busygina, Valeria, Alderman, Dawn, Kay, Brian K., Weiner, Michael P., Kiss, Margaret M.
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879119/
https://ncbi.nlm.nih.gov/pubmed/26607994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbt.2015.11.005
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