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Platform for High-Throughput Antibody Selection using Synthetically-Designed Antibody Libraries

Synthetic humanized antibody libraries are frequently generated by random incorporation of changes at multiple positions in the antibody hypervariable regions. Although these libraries have very large theoretical diversities (>10(20)), the practical diversity that can be achieved by transformatio...

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Détails bibliographiques
Publié dans:N Biotechnol
Auteurs principaux: Batonick, Melissa, Holland, Erika G., Busygina, Valeria, Alderman, Dawn, Kay, Brian K., Weiner, Michael P., Kiss, Margaret M.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879119/
https://ncbi.nlm.nih.gov/pubmed/26607994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbt.2015.11.005
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