High throughput discovery of influenza virus neutralizing antibodies from phage-displayed synthetic antibody libraries

Pandemic and epidemic outbreaks of influenza A virus (IAV) infection pose severe challenges to human society. Passive immunotherapy with recombinant neutralizing antibodies can potentially mitigate the threats of IAV infection. With a high throughput neutralizing antibody discovery platform, we prod...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Chen, Ing-Chien, Chiu, Yi-Kai, Yu, Chung-Ming, Lee, Cheng-Chung, Tung, Chao-Ping, Tsou, Yueh-Liang, Huang, Yi-Jen, Lin, Chia-Lung, Chen, Hong-Sen, Wang, Andrew H.-J., Yang, An-Suei
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5663709/
https://ncbi.nlm.nih.gov/pubmed/29089574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14823-w
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