Engineering Anti-vascular Endothelial Growth Factor Single Chain Disulfide-stabilized Antibody Variable Fragments (sc-dsFv) with Phage-displayed sc-dsFv Libraries

Phage display of antibody fragments from natural or synthetic antibody libraries with the single chain constructs combining the variable fragments (scFv) has been one of the most prominent technologies in antibody engineering. However, the nature of the artificial single chain constructs results in...

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Bibliografiske detaljer
Main Authors: Huang, Yi-Jen, Chen, Ing-Chien, Yu, Chung-Ming, Lee, Yu-Ching, Hsu, Hung-Ju, Ching, Anna Tung Ching, Chang, Hung-Ju, Yang, An-Suei
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Protein Synthesis and Degradation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832938/
https://ncbi.nlm.nih.gov/pubmed/20068035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061457
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