Engineering Anti-vascular Endothelial Growth Factor Single Chain Disulfide-stabilized Antibody Variable Fragments (sc-dsFv) with Phage-displayed sc-dsFv Libraries

Phage display of antibody fragments from natural or synthetic antibody libraries with the single chain constructs combining the variable fragments (scFv) has been one of the most prominent technologies in antibody engineering. However, the nature of the artificial single chain constructs results in...

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Main Authors: Huang, Yi-Jen, Chen, Ing-Chien, Yu, Chung-Ming, Lee, Yu-Ching, Hsu, Hung-Ju, Ching, Anna Tung Ching, Chang, Hung-Ju, Yang, An-Suei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832938/
https://ncbi.nlm.nih.gov/pubmed/20068035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061457
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