Engineering Anti-vascular Endothelial Growth Factor Single Chain Disulfide-stabilized Antibody Variable Fragments (sc-dsFv) with Phage-displayed sc-dsFv Libraries

Phage display of antibody fragments from natural or synthetic antibody libraries with the single chain constructs combining the variable fragments (scFv) has been one of the most prominent technologies in antibody engineering. However, the nature of the artificial single chain constructs results in...

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Autors principals: Huang, Yi-Jen, Chen, Ing-Chien, Yu, Chung-Ming, Lee, Yu-Ching, Hsu, Hung-Ju, Ching, Anna Tung Ching, Chang, Hung-Ju, Yang, An-Suei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2010
Matèries:
Protein Synthesis and Degradation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2832938/
https://ncbi.nlm.nih.gov/pubmed/20068035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.061457
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