The universally-conserved transcription factor RfaH is recruited to a hairpin structure of the non-template DNA strand

RfaH, a transcription regulator of the universally conserved NusG/Spt5 family, utilizes a unique mode of recruitment to elongating RNA polymerase to activate virulence genes. RfaH function depends critically on an ops sequence, an exemplar of a consensus pause, in the non-template DNA strand of the...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Zuber, Philipp K, Artsimovitch, Irina, NandyMazumdar, Monali, Liu, Zhaokun, Nedialkov, Yuri, Schweimer, Kristian, Rösch, Paul, Knauer, Stefan H
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2018
Assuntos:
Biochemistry and Chemical Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995543/
https://ncbi.nlm.nih.gov/pubmed/29741479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.36349
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