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Interdomain contacts control folding of transcription factor RfaH

Escherichia coli RfaH activates gene expression by tethering the elongating RNA polymerase to the ribosome. This bridging action requires a complete refolding of the RfaH C-terminal domain (CTD) from an α-helical hairpin, which binds to the N-terminal domain (NTD) in the free protein, to a β-barrel,...

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Autors principals: Tomar, Sushil Kumar, Knauer, Stefan H., NandyMazumdar, Monali, Rösch, Paul, Artsimovitch, Irina
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905879/
https://ncbi.nlm.nih.gov/pubmed/23990324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt779
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