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Interdomain Contacts Control Native State Switching of RfaH on a Dual-Funneled Landscape
RfaH is a virulence factor from Escherichia coli whose C-terminal domain (CTD) undergoes a dramatic α-to-β conformational transformation. The CTD in its α-helical fold is stabilized by interactions with the N-terminal domain (NTD), masking an RNA polymerase binding site until a specific recruitment...
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| Vydáno v: | PLoS Comput Biol |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4521827/ https://ncbi.nlm.nih.gov/pubmed/26230837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004379 |
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