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Differential Local Stability Governs the Metamorphic Fold Switch of Bacterial Virulence Factor RfaH

RfaH, a two-domain protein from a universally conserved NusG/Spt5 family of regulators, is required for the transcription and translation of long virulence and conjugation operons in many Gram-negative bacterial pathogens. Escherichia coli RfaH action is controlled by a unique large-scale structural...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Galaz-Davison, Pablo, Molina, José Alejandro, Silletti, Steve, Komives, Elizabeth A., Knauer, Stefan H., Artsimovitch, Irina, Ramírez-Sarmiento, César A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6950767/
https://ncbi.nlm.nih.gov/pubmed/31810657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2019.11.014
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