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An α-helix to β-barrel domain switch transforms the transcription factor RfaH into a translationfactor
NusG homologs regulate transcription and coupled processes in all living organisms. The Escherichia coli (E. coli) two-domain paralogs NusG and RfaH have conformationally identical N-terminal domains (NTDs) but dramatically different carboxy-terminal domains (CTDs), a β-barrel in NusG and an α-hairp...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430373/ https://ncbi.nlm.nih.gov/pubmed/22817892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.05.042 |
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