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RNA polymerase gate loop guides the nontemplate DNA strand in transcription complexes

Upon RNA polymerase (RNAP) binding to a promoter, the σ factor initiates DNA strand separation and captures the melted nontemplate DNA, whereas the core enzyme establishes interactions with the duplex DNA in front of the active site that stabilize initiation complexes and persist throughout elongati...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: NandyMazumdar, Monali, Nedialkov, Yuri, Svetlov, Dmitri, Sevostyanova, Anastasia, Belogurov, Georgiy A., Artsimovitch, Irina
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206560/
https://ncbi.nlm.nih.gov/pubmed/27956639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613673114
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