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Locking the non-template DNA to control transcription
Universally conserved NusG/Spt5 factors reduce RNA polymerase pausing and arrest. In a widely accepted model, these proteins bridge the RNA polymerase clamp and lobe domains across the DNA channel, inhibiting the clamp opening to promote pause-free RNA synthesis. However, recent structures of paused...
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| Publicado no: | Mol Microbiol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6173972/ https://ncbi.nlm.nih.gov/pubmed/29758107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.13983 |
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