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RNA polymerase gate loop guides the nontemplate DNA strand in transcription complexes

Upon RNA polymerase (RNAP) binding to a promoter, the σ factor initiates DNA strand separation and captures the melted nontemplate DNA, whereas the core enzyme establishes interactions with the duplex DNA in front of the active site that stabilize initiation complexes and persist throughout elongati...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: NandyMazumdar, Monali, Nedialkov, Yuri, Svetlov, Dmitri, Sevostyanova, Anastasia, Belogurov, Georgiy A., Artsimovitch, Irina
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206560/
https://ncbi.nlm.nih.gov/pubmed/27956639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1613673114
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