The ER membrane protein complex interacts cotranslationally to enable biogenesis of multipass membrane proteins

The endoplasmic reticulum (ER) supports biosynthesis of proteins with diverse transmembrane domain (TMD) lengths and hydrophobicity. Features in transmembrane domains such as charged residues in ion channels are often functionally important, but could pose a challenge during cotranslational membrane...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Shurtleff, Matthew J, Itzhak, Daniel N, Hussmann, Jeffrey A, Schirle Oakdale, Nicole T, Costa, Elizabeth A, Jonikas, Martin, Weibezahn, Jimena, Popova, Katerina D, Jan, Calvin H, Sinitcyn, Pavel, Vembar, Shruthi S, Hernandez, Hilda, Cox, Jürgen, Burlingame, Alma L, Brodsky, Jeffrey L, Frost, Adam, Borner, Georg HH, Weissman, Jonathan S
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2018
Ämnen:
Cell Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5995541/
https://ncbi.nlm.nih.gov/pubmed/29809151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37018
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