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One step at a time: endoplasmic reticulum-associated degradation

Protein folding in the endoplasmic reticulum (ER) is monitored by ER quality control (ERQC) mechanisms. Proteins that pass ERQC criteria traffic to their final destinations through the secretory pathway, whereas non-native and unassembled subunits of multimeric proteins are degraded by the ER-associ...

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Detalles Bibliográficos
Main Authors: Vembar, Shruthi S., Brodsky, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654601/
https://ncbi.nlm.nih.gov/pubmed/19002207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2546
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