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Cleaning Up: Endoplasmic Reticulum Associated Degradation to the Rescue
All cellular proteins are subject to quality control “decisions”, which helps prevent or delay a myriad of diseases. Quality control within the secretory pathway creates a special challenge, as aberrant polypeptides are recognized and returned to the cytoplasm for proteasomal degradation. This proce...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3521611/ https://ncbi.nlm.nih.gov/pubmed/23217703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.11.012 |
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