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One step at a time: endoplasmic reticulum-associated degradation
Protein folding in the endoplasmic reticulum (ER) is monitored by ER quality control (ERQC) mechanisms. Proteins that pass ERQC criteria traffic to their final destinations through the secretory pathway, whereas non-native and unassembled subunits of multimeric proteins are degraded by the ER-associ...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2654601/ https://ncbi.nlm.nih.gov/pubmed/19002207 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2546 |
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